Orienting memories during wake and sleep

Spatial navigation and memory formation are intrinsically linked. In the hippocampus, neuronal patterns that map an animal's trajectories during wakefulness are replayed during non-REM sleep, a process crucial for memory consolidation. Upstream of the hippocampus, the head-direction (HD) circuit provides a key input signal for navigation, yet its contribution to navigation and memory during sleep remains unclear. Here, I will present evidence that the HD system maintains its internal coherence and an environment-specific orientation memory over weeks.

Innate development of cognitive computations and motor programs by chemoaffinity

Abstract : Humans and animals are equipped with a rich innate repertoire of cognitive and behavioral skills. Yet, the developmental programs that establish the underlying neural structures are unknown. During early development, neural connectivity is often shaped by molecular programs that connect neurons based on the affinity between presynaptic receptors and postsynaptic ligands.

Precision functional mapping of the language and executive networks: implications for aging, stroke recovery, and targeted neuromodulation

Abstract: Association cortex is organized into multiple juxtaposed large-scale distributed networks that support higher-order cognition in humans, including language and cognitive control. A prominent view holds that these networks become less segregated, or reorganize, in healthy aging and after brain injury. In this talk, I will argue that this apparent reorganization may instead partly reflect the loss of each individual's idiosyncratic network topography when adjacent networks measured with fMRI are averaged across individuals.

Les fondements mécanistiques des biais sociaux (Projet SO-BIAS)

L'étude des mécanismes cognitifs impliqués dans l’expression et le contrôle des biais racistes, sexistes et intersectionnels

Bien que les enquêtes sociales indiquent que les attitudes racistes et sexistes sont en recul, les faits montrent que la discrimination et les inégalités persistent. La cause de ce phénomène est à la fois structurelle et individuelle : les inégalités structurelles sont reproduites de manière involontaire par les comportements individuels, guidés par des associations implicites.

Imprecise Number Representation and Economic Decisions

Economic decisions observed in the laboratory fail to conform to normative principles in a variety of respects. Among others, they are not even consistent with fixed preferences from trial to trial; in this respect, choices (for example, between simple gambles) resemble perceptual judgments. In this talk, I explore the possibility that some of the departures from normative choice behavior result from choices being based on imprecise semantic representations of the numbers used to specify monetary payoffs.

Electrophysiological characterization of auditory memory reactivations in the ferret

How the brain consolidates auditory memories during sleep remains poorly understood. A key open question is whether the hippocampus contributes to this process via sharp-wave ripple (SWR) events, the fast oscillatory sequences that drive memory replay in spatial tasks, or whether auditory cortex operates through distinct, cortex-intrinsic mechanisms. Addressing this question requires combining large-scale recordings across the auditory system and hippocampus with reliable vigilance-state monitoring.

Re-venir au monde. Pour une philosophie clinique multidimensionnelle du psychotraumatisme à la lumière des dispositifs technologiques d'immersion

Résumé. Je m’attacherai à présenter, dans cette conférence, ma recherche doctorale. Celle-ci défend une approche interdisciplinaire et multidimensionnelle du psychotraumatisme, réinterrogeant les articulations entre les données en première personne (dans une perspective phénoménologique) et en troisième personne (dans une perspective neuroscientifique cognitive).